Port Adelaide Power and Melbourne Demons have met 21 times — Port Adelaide Power won 13, Melbourne Demons won 8, with 0 draws. Port Adelaide Power leads the head-to-head with 13 victories from 21 meetings. A combined 3320 goals have been scored across these fixtures, averaging 158.10 per match (1719 for the home side, 1601 for the visitors). Both teams scored in 21 matches (100%). Over 2.5 goals landed in 21 games (100%), making it a fixture that tends to produce goals. Port Adelaide Power are currently unbeaten in the last 5 meetings. The highest-scoring encounter finished 112–104 in .